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A thematic course exploring five fundamental features of all biological systems, including structure and function, information flow, energy and matter, interactions, and evolution. This section will provide an introduction to disease ecology, with emphasis on environmental change, emerging infectious diseases, and zoonotic pathogens. We will discuss fundamental concepts in biology through examination of the genetic and physiological underpinnings of disease, the effects of disease on wildlife populations and behavior, and host-parasite co-evolution.