DCF94280-E8F7-F166-A62F886D097067AC
DD04824B-E24D-15F5-A605E08D0ABF4F66

Chemistry

The Senior Program

All senior chemistry students work collaboratively with faculty members on research projects as part of the Senior Program. This intensive two-semester project combines original scientific research with reading and understanding the scientific literature. It culminates in a Senior Thesis that is defended in a public presentation to departmental faculty and student chemistry majors.

Recent projects in chemistry include:

  • Competitive Ring Opening of a Series of 2,3-Diaryl-substituted Cyclopropylcarbinyl Radicals
  • Radical Cascade Synthesis of Substituted Bicyclo[3.3.0]octane Derivatives via Nickel(II)-catalyzed Cross Coupling Reactions of sp3 Carbon Centers
  • Development of New Oxygen-Mediated C-C Coupling Reactions
  • The Untapped Resource of Marine Natural Products: Cyanobacteria & Microorganisms & Attempts at the Synthesis of the (E)-11,16-Dichlorohexadec-4-enoic Acid of Dichlorobouillonamide for Chiral Characterization
  • Formation of 5,5,5-Tricyclic Ring Systems from [3.0.1]-Bicyclic Ring Systems via Radical Cascade Reaction
  • Expression and Purification of Isotopically Labelled Piscidin-1 for NMR Studies
  • Synthesis of Nanocrystalline Eu(TTA)3•3H2O and Incorporation in to Sol-Gels
  • Salicylate Chelates of Europium and Terbium Incorporated into Sol-Gel Silica Glasses
  • Towards the Synthesis of Cryptomaldamide, Diastereomers, and Analogs: The Algorithm for Tripeptide Formation
  • Investigation of the Effects of Electronic Desolvation on Oseltamivir Binding Kinetics to N1 Influenza Neuraminidase
  • Study of Piscidin 1 in Models of Cancer Cell Membranes and Healthy Mammalian Cell Membranes
  • The Diurnal Variation of Biomarkers in Human Urine
  • Radical-Mediated Ring Expansion to 7-5 Bicyclic Systems: The Synthesis of Bicyclo[4.2.1]nonane Derivatives via Endocyclic Cyclopropane Fragmentation and Cyclization onto External Olefins
  • Lanthanide Complex-Doped Sol-Gel Glasses Prepared by Post Annealing Immersion
  • The Synthesis of Both Enantiomers of 2-((tert-Butoxycarbonyl)(methyl)amino)-3-methoxypropyl Acetate: New Serinol Derivatives & A Brief Review of Anticancer Drug Agents Derived from Cyanobacteria Secondary Metabolites
  • Synthesis of Dinitrogen Molybdenum Complex Using Nitrogen-Based Ligands: A Pre-catalyst for Olefin Metathesis
  • Enhancing the Selectivity of β-L-Rhamnosidic Linkages Using Sulfonate Directing Groups
  • Progress on the Synthesis of a Repeating Unit of Pneumococcal Serotype 31
  • Progress on the Synthesis of Tri-, Tetra- and Pentasaccharide Derivatives of Trehalose for Preservation Studies
  • How do the Molecular Features of Neuropeptide Y and Lipid Bilayers Affect Each Other?
  • Synthesis and Luminescent Properties of Eu(TTA)3Ÿ3H2O Nanocrystallites in Sol-gel Derived Materials
  • Radical Expansion to Seven-Membered Bicyclic Systems
  • Progress on the Synthesis of Carbohydrate-Porphyrin Conjugates Using Click Chemistry
  • Formation of Tricyclic Systems via Radical Cascade Reactions
  • Competitive Ring Opening of Diaryl Substituted Cyclopropylcarbinyl Radicals
  • Synthesis of P-Stereogenic Water-Soluble Phosphines for Enantioselective Liquid-Liquid Extraction
  • Synthesis of the Serinol Portion of Dichlorobouillonaminde
  • Hydrated N2 and O2, Complexes: Implications of Weakly Bound Species in Atmospheric Chemistry
  • Controlling the Stereochemistry of Ylide Cyclopropanation Reactions iwth Amide Chiral Auxiliaries
  • Synthesis of Europium-Doped Yttria Nano-Particles and Their Incorporation into a Sol-Gel Glass Matrix
  • Characterization of a Novel Diiron Complex
  • Catecholase Activities Associated with Two Small Copper Proteins from Bovine Brain: Neurocuprein and S100b
  • A pH Profile of the Catalase Activity Associated with Ribonucleotide Reductase
  • Isothermal Titration Calorimetric Studies of Calcium Binding
  • Isolation and Characterization of a Novel Mollusc Hemoglobin
  • Sol-Gel Encapsolation of Proteins
  • Peroxide Activation of the Metal Clusters in the R2 Subunit of Escherichia coli Ribonucleotide Reductase
  • Probing the Catalase Activity of E. coli Ribonucleotide Reductase
  • Isolation of a Manganese-Containing Catalase from Thermus Thermophilus
  • The Purification and Chemistry of Neurocuprein from Bovine Brain
  • Manganese(II)-Reconstituted R2 from Ribonucleotide Reductase: A Structural and Functional Model of Mn-Catalases
  • Copper Binding to Ribonucleotide Reductase
  • The Synthesis of an Aziridinylmethyl Free Radical Precursor
  • Antifeedant Tannins of Acer rubrum
  • Further Investigation Into the Constituents of the Sea Sponge Stylotella aurantium
  • Isolation and Structure Elucidation of Natural Products from Aster Species
  • Probing for Electronic Effects in the Transition State of the Cyclopropylcarbinyl Radical Ring Opening Reaction
  • Stereoselective Allylation of Tertiary Radicals: Ester versus Amide Chiral Auxiliaries
  • Preparation of Titania-Silica Glasses Doped with Rare Earth Cations
  • A General Synthesis for Pyrrolidine Alkaloids by way of a Cascade Free Radical Reaction
  • The Application of Electrostatic Potential to Drug Design A pH Profile of the Catalase Activity Associated with Ribonucleotide Reductase
  • A Further Investigation Into the Constituents of the Sea Sponge Stylotella aurantium Peroxide Activation of the Metal Clusters in the R2 Subunit of Escherichia coli Ribonucleotide Reductase
  • Determination of Total Phenolic Content and Chemical Investigation of Red Maple Bark, Acer rubrum Sol-Gel Encapsolation of Proteins
  • The Basic Decomposition of Palau'amine and the Search for Biologically Active Compounds in Stylotella aurantium
  • Isothermal Titration Calorimetric Studies of Calcium Binding
  • Isolation and Characterization of a Novel Mollusc Hemoglobin
  • Isolation and Structure Elucidation of Natural Products from Aster Species Isolation of a Manganese-Containing Catalase from Thermus Thermophilus
  • Manganese(II)-Reconstituted R2 from Ribonucleotide Reductase: A
    Structural and Functional Model of Mn-Catalases
  • Probing the Catalase Activity of E. coli Ribonucleotide Reductase
  • The Purification and Chemistry of Neurocuprein from Bovine Brain
  • The Synthesis of an Aziridinylmethyl Free Radical Precursor
Cupola